| 1. Round | 01/08/2015 | Rot-Weiss Essen | - | SC Wiedenbrück | 0:3 | ||||
| 5. Round | 25/08/2015 | Rot-Weiss Essen | - | TuS Erndtebrück | 9:1 | ||||
| 6. Round | 01/09/2015 | SG Wattenscheid 09 | - | Rot-Weiss Essen | 3:0 | ||||
| 7. Round | 04/09/2015 | Rot-Weiss Essen | - | FC Wegberg-Beeck | 1:0 | ||||
| 8. Round | 12/09/2015 | SSVg Velbert | - | Rot-Weiss Essen | 0:1 | ||||
| 2. Round | 16/09/2015 | 1. FC Köln II | - | Rot-Weiss Essen | 2:0 | ||||
| 9. Round | 19/09/2015 | Bor. Mönchengladbach II | - | Rot-Weiss Essen | 3:1 | ||||
| 10. Round | 22/09/2015 | Rot-Weiss Essen | - | Fortuna Düsseldorf II | 3:2 | ||||
| 33. Round | 08/04/2016 | Rot Weiss Ahlen | - | Rot-Weiss Essen | 1:2 | ||||
| 24. Round | 12/04/2016 | TuS Erndtebrück | - | Rot-Weiss Essen | 1:0 | ||||
| 34. Round | 17/04/2016 | Rot-Weiss Essen | - | Alemannia Aachen | 3:2 | ||||
| 35. Round | 23/04/2016 | FC Schalke 04 II | - | Rot-Weiss Essen | 0:0 | ||||
| 27. Round | 27/04/2016 | Rot-Weiss Essen | - | SSVg Velbert | 3:2 | ||||
| 36. Round | 07/05/2016 | Rot-Weiss Essen | - | Rot-Weiß Oberhausen | 0:2 | ||||
| 37. Round | 14/05/2016 | FC Kray | - | Rot-Weiss Essen | 2:3 | ||||
| 38. Round | 21/05/2016 | Rot-Weiss Essen | - | Borussia Dortmund II | 2:1 |
Germany