| 1. Round | 10/08/2007 | FC St. Pauli | - | 1. FC Köln | 0:2 | ||||
| 4. Round | 31/08/2007 | TSV 1860 München | - | 1. FC Köln | 1:1 | ||||
| 5. Round | 16/09/2007 | 1. FC Köln | - | SpVgg Greuther Fürth | 0:0 |  |
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| 6. Round | 23/09/2007 | TuS Koblenz | - | 1. FC Köln | 1:2 | |
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| 7. Round | 26/09/2007 | 1. FC Köln | - | SC Freiburg | 1:3 | |
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| 8. Round | 30/09/2007 | SV Wehen Wiesbaden | - | 1. FC Köln | 4:3 | ||||
| 10. Round | 22/10/2007 | Bor. Mönchengladbach | - | 1. FC Köln | 2:2 | ||||
| 11. Round | 28/10/2007 | 1. FC Köln | - | SC Paderborn 07 | 2:1 | ||||
| 13. Round | 09/11/2007 | 1. FC Köln | - | Erzgebirge Aue | 3:2 | ||||
| 21. Round | 22/02/2008 | 1. FC Köln | - | TSV 1860 München | 0:0 | ||||
| 22. Round | 29/02/2008 | SpVgg Greuther Fürth | - | 1. FC Köln | 2:2 | ||||
| 23. Round | 09/03/2008 | 1. FC Köln | - | TuS Koblenz | 1:0 | ||||
| 30. Round | 25/04/2008 | Erzgebirge Aue | - | 1. FC Köln | 3:3 | ||||
| 31. Round | 04/05/2008 | 1. FC Köln | - | 1899 Hoffenheim | 3:1 | |
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| 32. Round | 07/05/2008 | FC Augsburg | - | 1. FC Köln | 1:3 | ||||
| 33. Round | 11/05/2008 | 1. FC Köln | - | 1. FSV Mainz 05 | 2:0 |
Honduras