1. Round | 26/07/2021 | Barcelona | - | Manta | 2:0 | ||||
3. Round | 08/08/2021 | Barcelona | - | Guayaquil City | 2:1 | ||||
4. Round | 15/08/2021 | Orense SC | - | Barcelona | 1:0 | ||||
6. Round | 30/08/2021 | Independiente del Valle | - | Barcelona | 1:0 | ||||
9. Round | 03/10/2021 | Barcelona | - | Mushuc Runa | 4:0 | ||||
11. Round | 25/10/2021 | Emelec | - | Barcelona | 2:1 | ||||
8. Round | 28/10/2021 | Aucas | - | Barcelona | 1:0 |