1. Round | 24/07/2021 | FK Pardubice | - | MFK Karviná | 2:2 | ||||
2. Round | 31/07/2021 | MFK Karviná | - | FC Hradec Králové | 1:1 | ||||
3. Round | 07/08/2021 | AC Sparta Praha | - | MFK Karviná | 2:0 | ||||
5. Round | 22/08/2021 | Viktoria Plzeň | - | MFK Karviná | 2:0 | ||||
15. Round | 21/11/2021 | MFK Karviná | - | Slovan Liberec | 1:2 | ||||
12. Round | 24/11/2021 | MFK Karviná | - | Baník Ostrava | 1:2 | ||||
13. Round | 01/12/2021 | Bohemians Praha 1905 | - | MFK Karviná | 3:0 |