| 1. Round | 15/08/2004 | FC Groningen | - | RKC Waalwijk | 0:0 | ||||
| 2. Round | 20/08/2004 | Vitesse | - | FC Groningen | 1:0 | ||||
| 3. Round | 29/08/2004 | RBC Roosendaal | - | FC Groningen | 2:2 |  |
|||
| 11. Round | 07/11/2004 | FC Twente | - | FC Groningen | 1:2 | ||||
| 16. Round | 10/12/2004 | sc Heerenveen | - | FC Groningen | 1:0 | ||||
| 17. Round | 19/12/2004 | FC Groningen | - | AFC Ajax | 0:4 | ||||
| 19. Round | 30/01/2005 | FC Groningen | - | De Graafschap | 1:0 | ||||
| 21. Round | 11/02/2005 | FC Groningen | - | Vitesse | 0:0 |  |
|||
| 22. Round | 20/02/2005 | FC Groningen | - | FC Twente | 0:1 | ||||
| 24. Round | 17/03/2005 | FC Groningen | - | PSV Eindhoven | 0:1 | ||||
| 26. Round | 20/03/2005 | FC Groningen | - | Willem II | 1:1 | ||||
| 27. Round | 03/04/2005 | NEC Nijmegen | - | FC Groningen | 4:3 | ||||
| 28. Round | 09/04/2005 | FC Groningen | - | RBC Roosendaal | 3:0 | ||||
| 29. Round | 17/04/2005 | FC Den Bosch | - | FC Groningen | 1:2 | ||||
| 30. Round | 24/04/2005 | FC Groningen | - | Feyenoord | 0:2 | |
|||
| 31. Round | 01/05/2005 | AZ Alkmaar | - | FC Groningen | 2:1 | ||||
| 32. Round | 08/05/2005 | FC Groningen | - | Roda JC Kerkrade | 4:4 | |
|||
| 33. Round | 15/05/2005 | FC Groningen | - | sc Heerenveen | 1:2 | |
Netherlands