| 4. Round | 21/08/2022 | FC Bălţi | - | FC Sheriff | 0:3 | ||||
| 5. Round | 29/08/2022 | FC Sheriff | - | CS Petrocub | 1:1 | ||||
| 7. Round | 11/09/2022 | FC Sheriff | - | FC Milsami | 2:0 | ||||
| 9. Round | 02/10/2022 | FC Sheriff | - | FC Sfîntul Gheorghe | 3:0 | ||||
| 13. Round | 30/10/2022 | FC Sheriff | - | Dacia Buiucani | 2:1 |  |
Ukraine