| 1. Round | 11/11/2017 | AFC Tubize | - | Lierse SK | 1:2 | ||||
| 2. Round | 17/11/2017 | Lierse SK | - | Cercle Brugge | 1:0 | ||||
| 3. Round | 25/11/2017 | KSV Roeselare | - | Lierse SK | 1:2 | ||||
| 4. Round | 02/12/2017 | Lierse SK | - | KVC Westerlo | 2:0 | ||||
| 5. Round | 09/12/2017 | Union Saint-Gilloise | - | Lierse SK | 1:0 |  |
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| 6. Round | 15/12/2017 | Oud-Heverlee Leuven | - | Lierse SK | 2:1 | ||||
| 9. Round | 19/01/2018 | Cercle Brugge | - | Lierse SK | 4:1 | ||||
| 12. Round | 11/02/2018 | Lierse SK | - | Oud-Heverlee Leuven | 0:1 | ||||
| 13. Round | 16/02/2018 | Lierse SK | - | KSV Roeselare | 1:2 |
Belgium