| 1. Round | 16/07/2016 | Club Tijuana | - | Monarcas Morelia | 2:0 |  |
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| 2. Round | 25/07/2016 | Puebla FC | - | Club Tijuana | 3:2 | ||||
| 3. Round | 30/07/2016 | Club Tijuana | - | Deportivo Guadalajara | 4:0 | ||||
| 5. Round | 13/08/2016 | Club Tijuana | - | Club León | 2:0 | ||||
| 6. Round | 21/08/2016 | Club Necaxa | - | Club Tijuana | 1:1 | ||||
| 8. Round | 11/09/2016 | CF Monterrey | - | Club Tijuana | 0:0 | ||||
| 9. Round | 18/09/2016 | CF Pachuca | - | Club Tijuana | 2:2 | ||||
| 11. Round | 26/09/2016 | Santos Laguna | - | Club Tijuana | 1:2 | ||||
| 12. Round | 01/10/2016 | Club Tijuana | - | Atlas Guadalajara | 1:0 | ||||
| 14. Round | 22/10/2016 | Club Tijuana | - | Chiapas FC | 2:0 | ||||
| 15. Round | 30/10/2016 | Deportivo Toluca | - | Club Tijuana | 0:1 | ||||
| 16. Round | 05/11/2016 | Club Tijuana | - | UANL Tigres | 0:1 | ||||
| 17. Round | 19/11/2016 | CD Veracruz | - | Club Tijuana | 2:1 |
Mexico