| 1. Round | 08/08/2009 | Grenoble Foot 38 | - | Olympique Marseille | 0:2 | ||||
| 2. Round | 16/08/2009 | US Boulogne | - | Grenoble Foot 38 | 2:1 | ||||
| 3. Round | 23/08/2009 | Grenoble Foot 38 | - | RC Lens | 1:2 | ||||
| 4. Round | 29/08/2009 | AS Saint-Étienne | - | Grenoble Foot 38 | 1:0 |  |
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| 20. Round | 16/01/2010 | Grenoble Foot 38 | - | AS Saint-Étienne | 1:2 | ||||
| 24. Round | 13/02/2010 | Montpellier HSC | - | Grenoble Foot 38 | 1:0 | ||||
| 25. Round | 20/02/2010 | Grenoble Foot 38 | - | Valenciennes FC | 0:1 | ||||
| 26. Round | 27/02/2010 | AS Nancy Lorraine | - | Grenoble Foot 38 | 0:2 | ||||
| 27. Round | 07/03/2010 | Grenoble Foot 38 | - | Le Mans UC 72 | 1:1 | ||||
| 31. Round | 03/04/2010 | Grenoble Foot 38 | - | FC Lorient | 1:2 | ||||
| 32. Round | 10/04/2010 | Toulouse FC | - | Grenoble Foot 38 | 4:0 | ||||
| 35. Round | 27/04/2010 | Grenoble Foot 38 | - | Paris Saint-Germain | 4:0 | ||||
| 36. Round | 05/05/2010 | RC Lens | - | Grenoble Foot 38 | 1:1 | ||||
| 37. Round | 08/05/2010 | Grenoble Foot 38 | - | US Boulogne | 2:0 |
Croatia