| Group B | 15/09/2021 | Atlético Madrid | - | FC Porto | 0:0 | ||||
| Group B | 28/09/2021 | AC Milan | - | Atlético Madrid | 1:2 | ||||
| Group B | 19/10/2021 | Atlético Madrid | - | Liverpool FC | 2:3 | ||||
| Group B | 03/11/2021 | Liverpool FC | - | Atlético Madrid | 2:0 | ||||
| Group B | 24/11/2021 | Atlético Madrid | - | AC Milan | 0:1 | ||||
| Round of 16 | 23/02/2022 | Atlético Madrid | - | Manchester United | 1:1 |  |
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| Round of 16 | 15/03/2022 | Manchester United | - | Atlético Madrid | 0:1 |
Uruguay
Spain 
