| 1. Round | 10/08/2018 | Olympique Marseille | - | Toulouse FC | 4:0 | ||||
| 2. Round | 19/08/2018 | Toulouse FC | - | Girondins Bordeaux | 2:1 | ||||
| 3. Round | 25/08/2018 | Toulouse FC | - | Nîmes Olympique | 1:0 | ||||
| 5. Round | 15/09/2018 | Toulouse FC | - | AS Monaco | 1:1 | ||||
| 6. Round | 22/09/2018 | Angers SCO | - | Toulouse FC | 0:0 | ||||
| 7. Round | 25/09/2018 | Toulouse FC | - | AS Saint-Étienne | 2:3 | ||||
| 8. Round | 30/09/2018 | Stade Rennais | - | Toulouse FC | 1:1 | ||||
| 11. Round | 27/10/2018 | Toulouse FC | - | Montpellier HSC | 0:3 | ||||
| 12. Round | 03/11/2018 | RC Strasbourg | - | Toulouse FC | 1:1 | ||||
| 14. Round | 24/11/2018 | Paris Saint-Germain | - | Toulouse FC | 1:0 | ||||
| 20. Round | 13/01/2019 | Toulouse FC | - | RC Strasbourg | 1:2 |  |
|||
| 23. Round | 02/02/2019 | AS Monaco | - | Toulouse FC | 2:1 | ||||
| 31. Round | 07/04/2019 | Toulouse FC | - | FC Nantes | 1:0 | ||||
| 35. Round | 05/05/2019 | Toulouse FC | - | Stade Rennais | 2:2 | ||||
| 36. Round | 11/05/2019 | Amiens SC | - | Toulouse FC | 0:0 | ||||
| 37. Round | 18/05/2019 | Toulouse FC | - | Olympique Marseille | 2:5 |
England