| 1. Round | 07/08/2022 | West Ham United | - | Manchester City | 0:2 |  |
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| 2. Round | 13/08/2022 | Manchester City | - | AFC Bournemouth | 4:0 | ||||
| 3. Round | 21/08/2022 | Newcastle United | - | Manchester City | 3:3 | |
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| 4. Round | 27/08/2022 | Manchester City | - | Crystal Palace | 4:2 | ||||
| 5. Round | 31/08/2022 | Manchester City | - | Nottingham Forest | 6:0 |  |
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| 6. Round | 03/09/2022 | Aston Villa | - | Manchester City | 1:1 | ||||
| 8. Round | 17/09/2022 | Wolverhampton Wanderers | - | Manchester City | 0:3 | ||||
| 9. Round | 02/10/2022 | Manchester City | - | Manchester United | 6:3 | ||||
| 10. Round | 08/10/2022 | Manchester City | - | Southampton FC | 4:0 | |
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| 11. Round | 16/10/2022 | Liverpool FC | - | Manchester City | 1:0 | ||||
| 13. Round | 22/10/2022 | Manchester City | - | Brighton & Hove Albion | 3:1 | ||||
| 14. Round | 29/10/2022 | Leicester City | - | Manchester City | 0:1 | ||||
| 15. Round | 05/11/2022 | Manchester City | - | Fulham FC | 2:1 |  |
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| 16. Round | 12/11/2022 | Manchester City | - | Brentford FC | 1:2 | |
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| 17. Round | 28/12/2022 | Leeds United | - | Manchester City | 1:3 | ||||
| 19. Round | 05/01/2023 | Chelsea FC | - | Manchester City | 0:1 | ||||
| 20. Round | 14/01/2023 | Manchester United | - | Manchester City | 2:1 |
Portugal
