| 4. Round | 09/08/2021 | Radnički Niš | - | TSC Bačka Topola | 1:2 | ||||
| 7. Round | 29/08/2021 | Partizan | - | Radnički Niš | 4:0 |  |
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| 12. Round | 03/10/2021 | Vojvodina | - | Radnički Niš | 1:1 | |
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| 14. Round | 24/10/2021 | Crvena Zvezda | - | Radnički Niš | 1:0 | ||||
| 15. Round | 30/10/2021 | Radnički Niš | - | Mladost Lučani | 2:0 |
Serbia