| 15. Round | 28/08/2022 | Henan Songshan Longmen | - | Guangzhou FC | 2:1 |  |
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| 12. Round | 01/09/2022 | Zhejiang Professional | - | Guangzhou FC | 3:0 | ||||
| 17. Round | 09/09/2022 | Guangzhou FC | - | Tianjin Jinmen Tiger | 0:0 | ||||
| 21. Round | 05/10/2022 | Changchun Yatai | - | Guangzhou FC | 0:0 | ||||
| 22. Round | 09/10/2022 | Guangzhou FC | - | Meizhou Hakka | 1:3 | ||||
| 19. Round | 24/10/2022 | Guangzhou FC | - | Shandong Taishan | 0:3 | ||||
| 20. Round | 29/10/2022 | Beijing Guoan | - | Guangzhou FC | 4:1 | ||||
| 23. Round | 04/11/2022 | Guangzhou FC | - | Cangzhou Mighty Lions | 3:3 | ||||
| 24. Round | 08/11/2022 | Guangzhou FC | - | Zhejiang Professional | 1:5 | ||||
| 25. Round | 13/11/2022 | Dalian Pro | - | Guangzhou FC | 1:1 | |
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| 26. Round | 22/11/2022 | Shenzhen FC | - | Guangzhou FC | 2:1 | ||||
| 27. Round | 26/11/2022 | Guangzhou FC | - | Henan Songshan Longmen | 1:1 | ||||
| 28. Round | 01/12/2022 | Chengdu Rongcheng | - | Guangzhou FC | 2:0 | ||||
| 30. Round | 10/12/2022 | Guangzhou FC | - | Guangzhou City | 0:0 | ||||
| 31. Round | 15/12/2022 | Shandong Taishan | - | Guangzhou FC | 4:2 |
China