| 6. Round | 18/07/2022 | Nashville SC | - | Los Angeles FC | 1:2 | ||||
| 6. Round | 24/07/2022 | Sporting Kansas City | - | Los Angeles FC | 0:2 |  |
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| 6. Round | 30/07/2022 | Los Angeles FC | - | Seattle Sounders | 2:1 | ||||
| 7. Round | 07/08/2022 | Real Salt Lake | - | Los Angeles FC | 1:4 | |
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| 7. Round | 21/08/2022 | San Jose Earthquakes | - | Los Angeles FC | 2:1 | ||||
| 7. Round | 27/08/2022 | Austin FC | - | Los Angeles FC | 4:1 | ||||
| 7. Round | 01/09/2022 | Houston Dynamo | - | Los Angeles FC | 2:1 | ||||
| 8. Round | 05/09/2022 | Los Angeles FC | - | Real Salt Lake | 2:0 | ||||
| 8. Round | 11/09/2022 | FC Dallas | - | Los Angeles FC | 2:1 | ||||
| 8. Round | 14/09/2022 | Minnesota United FC | - | Los Angeles FC | 1:1 | ||||
| 8. Round | 19/09/2022 | Los Angeles FC | - | Houston Dynamo | 3:1 | ||||
| 9. Round | 02/10/2022 | Portland Timbers | - | Los Angeles FC | 1:2 |
Wales
England 
