| 2. Round | 14/08/2016 | Lierse SK | - | Cercle Brugge | 2:0 | ||||
| 3. Round | 21/08/2016 | Union Saint-Gilloise | - | Lierse SK | 2:2 |  |
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| 4. Round | 02/09/2016 | Lierse SK | - | Oud-Heverlee Leuven | 2:2 | ||||
| 5. Round | 09/09/2016 | Royal Antwerp FC | - | Lierse SK | 1:2 | ||||
| 6. Round | 17/09/2016 | Lierse SK | - | AFC Tubize | 5:1 | |
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| 7. Round | 25/09/2016 | Lommel United | - | Lierse SK | 0:3 | ||||
| 8. Round | 02/10/2016 | Lierse SK | - | KSV Roeselare | 0:2 | ||||
| 9. Round | 06/10/2016 | Cercle Brugge | - | Lierse SK | 0:0 | ||||
| 10. Round | 09/10/2016 | Lierse SK | - | Royal Antwerp FC | 2:0 | ||||
| 11. Round | 15/10/2016 | Lierse SK | - | Union Saint-Gilloise | 2:1 | ||||
| 12. Round | 21/10/2016 | AFC Tubize | - | Lierse SK | 1:3 | ||||
| 14. Round | 06/11/2016 | Oud-Heverlee Leuven | - | Lierse SK | 0:1 |
Belgium