| 1. Round | 25/07/2021 | 1. FC Nürnberg | - | Erzgebirge Aue | 0:0 | ||||
| 2. Round | 30/07/2021 | SC Paderborn 07 | - | 1. FC Nürnberg | 2:2 |  |
|||
| 23. Round | 19/02/2022 | 1. FC Nürnberg | - | Jahn Regensburg | 2:0 | ||||
| 26. Round | 13/03/2022 | Hannover 96 | - | 1. FC Nürnberg | 0:3 | ||||
| 29. Round | 09/04/2022 | 1. FC Nürnberg | - | SV Darmstadt 98 | 3:1 | ||||
| 30. Round | 17/04/2022 | Werder Bremen | - | 1. FC Nürnberg | 1:1 | ||||
| 32. Round | 29/04/2022 | FC St. Pauli | - | 1. FC Nürnberg | 1:1 | ||||
| 33. Round | 08/05/2022 | Holstein Kiel | - | 1. FC Nürnberg | 3:0 | ||||
| 34. Round | 15/05/2022 | 1. FC Nürnberg | - | FC Schalke 04 | 1:2 | |
Germany