| 3. Round | 20/02/2022 | Academia Cantolao | - | Alianza Atlético | 1:3 | ||||
| 4. Round | 27/02/2022 | Alianza Atlético | - | Alianza Lima | 4:2 | ||||
| 5. Round | 06/03/2022 | Carlos Stein | - | Alianza Atlético | 0:1 | ||||
| 10. Round | 15/04/2022 | Alianza Atlético | - | Deportivo Binacional | 2:0 | ||||
| 12. Round | 01/05/2022 | Alianza Atlético | - | Ayacucho FC | 2:1 | ||||
| 13. Round | 07/05/2022 | Universitario de Deportes | - | Alianza Atlético | 3:1 | ||||
| 14. Round | 15/05/2022 | Alianza Atlético | - | Sport Boys | 1:2 | ||||
| 15. Round | 22/05/2022 | Atlético Grau | - | Alianza Atlético | 1:2 |  |
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| 16. Round | 30/05/2022 | Sport Huancayo | - | Alianza Atlético | 4:1 |
Peru