| 1. Round | 11/01/2025 | Deportivo Guadalajara [U19] | - | Santos Laguna [U19] | 3:0 | ||||
| 2. Round | 20/01/2025 | CF Pachuca [U19] | - | Santos Laguna [U19] | 2:1 | ||||
| 3. Round | 25/01/2025 | Santos Laguna [U19] | - | CF América [U19] | 3:0 | ||||
| 5. Round | 02/02/2025 | Santos Laguna [U19] | - | Puebla FC [U19] | 2:0 | ||||
| 7. Round | 14/02/2025 | Mazatlán FC [U19] | - | Santos Laguna [U19] | 3:0 | ||||
| 9. Round | 19/02/2025 | Santos Laguna [U19] | - | Cruz Azul [U19] | 1:0 | ||||
| 8. Round | 23/02/2025 | Santos Laguna [U19] | - | Atlas Guadalajara [U19] | 1:2 | ||||
| 16. Round | 22/03/2025 | Pumas UNAM [U19] | - | Santos Laguna [U19] | 3:2 | ||||
| 13. Round | 30/03/2025 | Santos Laguna [U19] | - | Atlético San Luis [U19] | 2:1 | ||||
| 14. Round | 06/04/2025 | Deportivo Toluca [U19] | - | Santos Laguna [U19] | 0:2 |
Mexico