| 13. Round | 25/10/1980 | Waldhof Mannheim | - | Wormatia Worms | 3:0 | ||||
| 14. Round | 30/10/1980 | Wormatia Worms | - | FSV Frankfurt | 2:1 | ||||
| 15. Round | 07/11/1980 | SV Darmstadt 98 | - | Wormatia Worms | 5:0 | ||||
| 16. Round | 14/11/1980 | Wormatia Worms | - | SC Freiburg | 2:2 |  |
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| 17. Round | 27/11/1980 | Hessen Kassel | - | Wormatia Worms | 4:2 | |
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| 18. Round | 05/12/1980 | Wormatia Worms | - | FC Augsburg | 3:1 | ||||
| 19. Round | 12/12/1980 | VfB Eppingen | - | Wormatia Worms | 2:0 | ||||
| 20. Round | 02/01/1981 | Eintracht Trier | - | Wormatia Worms | 1:0 | ||||
| 23. Round | 23/01/1981 | Wormatia Worms | - | Stuttgarter Kickers | 2:2 | ||||
| 26. Round | 20/02/1981 | Freiburger FC | - | Wormatia Worms | 3:1 | ||||
| 30. Round | 26/03/1981 | 1. FC Saarbrücken | - | Wormatia Worms | 2:1 | ||||
| 31. Round | 03/04/1981 | Wormatia Worms | - | FC 08 Homburg | 0:0 | ||||
| 24. Round | 07/04/1981 | ESV Ingolstadt | - | Wormatia Worms | 0:3 | |
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| 32. Round | 09/04/1981 | Wormatia Worms | - | Waldhof Mannheim | 3:2 | ||||
| 33. Round | 14/04/1981 | FSV Frankfurt | - | Wormatia Worms | 2:1 | ||||
| 34. Round | 23/04/1981 | Wormatia Worms | - | SV Darmstadt 98 | 0:0 | ||||
| 35. Round | 29/04/1981 | SC Freiburg | - | Wormatia Worms | 5:2 |
Germany