| 4. Round | 28/01/2023 | FC Juárez [U18] | - | Deportivo Guadalajara [U18] | 3:3 |  |
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| 5. Round | 05/02/2023 | Deportivo Guadalajara [U18] | - | Gallos Blancos [U18] | 4:0 | ||||
| 6. Round | 11/02/2023 | CF Pachuca [U18] | - | Deportivo Guadalajara [U18] | 2:2 |  |
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| 7. Round | 15/02/2023 | Deportivo Guadalajara [U18] | - | Club Tijuana [U18] | 1:2 | |
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| 8. Round | 18/02/2023 | Pumas UNAM [U18] | - | Deportivo Guadalajara [U18] | 0:1 | ||||
| 9. Round | 25/02/2023 | UANL Tigres [U18] | - | Deportivo Guadalajara [U18] | 1:1 | |
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| 10. Round | 04/03/2023 | Deportivo Guadalajara [U18] | - | Santos Laguna [U18] | 2:0 | |
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| 11. Round | 10/03/2023 | Puebla FC [U18] | - | Deportivo Guadalajara [U18] | 2:0 | ||||
| 12. Round | 18/03/2023 | Deportivo Guadalajara [U18] | - | CF América [U18] | 4:1 | ||||
| 13. Round | 01/04/2023 | Atlas Guadalajara [U18] | - | Deportivo Guadalajara [U18] | 2:3 | |
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| 14. Round | 08/04/2023 | Deportivo Guadalajara [U18] | - | Club Necaxa [U18] | 2:1 | |
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| 16. Round | 22/04/2023 | Deportivo Guadalajara [U18] | - | Cruz Azul [U18] | 1:1 | |
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| 17. Round | 29/04/2023 | Deportivo Guadalajara [U18] | - | Mazatlán FC [U18] | 3:0 |
Mexico