| 1. Round | 17/04/2021 | CF Montréal | - | Toronto FC | 4:2 | ||||
| 1. Round | 24/04/2021 | Nashville SC | - | CF Montréal | 2:2 | ||||
| 2. Round | 01/05/2021 | CF Montréal | - | Columbus Crew | 0:0 | ||||
| 2. Round | 08/05/2021 | Vancouver Whitecaps | - | CF Montréal | 2:0 | ||||
| 2. Round | 16/05/2021 | Atlanta United FC | - | CF Montréal | 1:0 | ||||
| 2. Round | 22/05/2021 | CF Montréal | - | FC Cincinnati | 1:2 | ||||
| 2. Round | 29/05/2021 | Chicago Fire | - | CF Montréal | 0:1 | ||||
| 3. Round | 24/06/2021 | CF Montréal | - | D.C. United | 0:0 |  |
France