| 2. Round | 13/11/2021 | APS Zakynthos | - | AO Egaleo | 0:1 | ||||
| 5. Round | 28/11/2021 | AS Rhodos | - | APS Zakynthos | 4:0 | ||||
| 8. Round | 15/12/2021 | APS Zakynthos | - | AEK Athen II | 0:0 | ||||
| 25. Round | 19/03/2022 | AEK Athen II | - | APS Zakynthos | 1:0 | ||||
| 27. Round | 30/03/2022 | Panathinaikos II | - | APS Zakynthos | 1:1 |
Portugal