| 7. Round | 10/01/2021 | US Ben Guerdane | - | CS Sfaxien | 1:0 | ||||
| 8. Round | 13/01/2021 | CS Sfaxien | - | Espérance de Tunis | 2:0 | ||||
| 11. Round | 31/01/2021 | AS Soliman | - | CS Sfaxien | 1:1 | ||||
| 12. Round | 03/02/2021 | JS Kairouan | - | CS Sfaxien | 0:4 | ||||
| 13. Round | 07/02/2021 | CS Sfaxien | - | AS Rejiche | 1:0 | ||||
| 4. Round | 16/02/2021 | Olympique Béja | - | CS Sfaxien | 1:0 | ||||
| 6. Round | 28/02/2021 | Étoile du Sahel | - | CS Sfaxien | 0:1 | ||||
| 15. Round | 04/03/2021 | CS Sfaxien | - | US Tataouine | 1:2 | ||||
| 16. Round | 07/03/2021 | Club Africain | - | CS Sfaxien | 0:0 | ||||
| 18. Round | 13/03/2021 | Stade Tunisien | - | CS Sfaxien | 1:0 | ||||
| 20. Round | 21/03/2021 | CS Sfaxien | - | US Ben Guerdane | 1:1 | ||||
| 14. Round | 24/03/2021 | US Monastir | - | CS Sfaxien | 0:0 | ||||
| 23. Round | 07/04/2021 | ES Métlaoui | - | CS Sfaxien | 0:1 | ||||
| 21. Round | 25/04/2021 | Espérance de Tunis | - | CS Sfaxien | 0:0 | ||||
| 22. Round | 02/05/2021 | CS Sfaxien | - | CA Bizertin | 0:0 | ||||
| 24. Round | 05/05/2021 | CS Sfaxien | - | AS Soliman | 0:1 | ||||
| 25. Round | 09/05/2021 | CS Sfaxien | - | JS Kairouan | 2:0 | ||||
| 26. Round | 19/05/2021 | AS Rejiche | - | CS Sfaxien | 3:3 |
Tunisia