2. Round 20/08/2021 UD Almería - Real Oviedo 2:1
3. Round 28/08/2021 Real Oviedo - CD Tenerife 0:0
4. Round 06/09/2021 SD Huesca - Real Oviedo 1:2 Goal yellow card
5. Round 12/09/2021 Real Oviedo - FC Cartagena 2:0 Goal yellow card
6. Round 18/09/2021 UD Ibiza - Real Oviedo 1:1
7. Round 26/09/2021 Real Oviedo - Girona FC 0:0
8. Round 02/10/2021 Real Zaragoza - Real Oviedo 0:0
9. Round 09/10/2021 Real Oviedo - Sporting Gijón 1:1
10. Round 17/10/2021 Real Sociedad B - Real Oviedo 1:1 Goal
11. Round 21/10/2021 Real Oviedo - Burgos CF 1:3 Goal
12. Round 24/10/2021 SD Ponferradina - Real Oviedo 1:2 Goal
13. Round 31/10/2021 Real Oviedo - Málaga CF 2:1 GoalGoal
14. Round 03/11/2021 SD Eibar - Real Oviedo 1:0
15. Round 06/11/2021 Real Oviedo - UD Las Palmas 1:1 Goal
16. Round 14/11/2021 CD Leganés - Real Oviedo 0:0
17. Round 20/11/2021 Real Oviedo - SD Amorebieta 2:0
18. Round 26/11/2021 CD Mirandés - Real Oviedo 1:1
19. Round 05/12/2021 Real Oviedo - AD Alcorcón 3:1 GoalGoal
20. Round 12/12/2021 Real Valladolid - Real Oviedo 2:1 Goal
21. Round 19/12/2021 CF Fuenlabrada - Real Oviedo 0:0
23. Round 10/01/2022 Real Oviedo - SD Eibar 1:1
24. Round 21/01/2022 CD Tenerife - Real Oviedo 4:0
25. Round 29/01/2022 Real Oviedo - UD Almería 2:0 Goal
26. Round 06/02/2022 SD Amorebieta - Real Oviedo 1:1 Goal
27. Round 13/02/2022 Real Oviedo - SD Huesca 3:3 Goal yellow card
28. Round 20/02/2022 Burgos CF - Real Oviedo 0:1 Goal
29. Round 26/02/2022 Real Oviedo - Real Sociedad B 0:1
30. Round 06/03/2022 Girona FC - Real Oviedo 2:1
31. Round 13/03/2022 Real Oviedo - Real Valladolid 3:0 Goal
32. Round 19/03/2022 CD Lugo - Real Oviedo 1:1 Goal
33. Round 26/03/2022 Real Oviedo - CF Fuenlabrada 3:0
34. Round 03/04/2022 FC Cartagena - Real Oviedo 1:2 yellow card
35. Round 10/04/2022 Real Oviedo - CD Leganés 1:0 Goal
36. Round 16/04/2022 Sporting Gijón - Real Oviedo 0:1
37. Round 24/04/2022 AD Alcorcón - Real Oviedo 1:2
38. Round 30/04/2022 Real Oviedo - CD Mirandés 3:0 Goal
39. Round 07/05/2022 Málaga CF - Real Oviedo 0:0
40. Round 16/05/2022 Real Oviedo - Real Zaragoza 3:3 Goal
41. Round 21/05/2022 UD Las Palmas - Real Oviedo 2:1
42. Round 29/05/2022 Real Oviedo - UD Ibiza 3:2 GoalGoal