| 1. Round | 28/01/2012 | Huachipato | - | Santiago Wanderers | 2:1 | ||||
| 2. Round | 04/02/2012 | Santiago Wanderers | - | Universidad Católica | 2:1 | ||||
| 3. Round | 12/02/2012 | Rangers | - | Santiago Wanderers | 2:3 |  |
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| 4. Round | 18/02/2012 | Santiago Wanderers | - | Audax Italiano | 4:2 | ||||
| 6. Round | 04/03/2012 | Santiago Wanderers | - | Colo-Colo | 0:0 | ||||
| 7. Round | 11/03/2012 | Antofagasta | - | Santiago Wanderers | 1:0 | ||||
| 8. Round | 16/03/2012 | Santiago Wanderers | - | Unión San Felipe | 1:0 | ||||
| 9. Round | 23/03/2012 | Universidad de Concepción | - | Santiago Wanderers | 2:5 | |
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| 10. Round | 31/03/2012 | Santiago Wanderers | - | Cobresal | 5:2 | ||||
| 11. Round | 08/04/2012 | Universidad de Chile | - | Santiago Wanderers | 3:0 | ||||
| 12. Round | 14/04/2012 | Palestino | - | Santiago Wanderers | 2:1 | ||||
| 13. Round | 21/04/2012 | Santiago Wanderers | - | Unión Española | 2:2 | ||||
| 14. Round | 29/04/2012 | Santiago Wanderers | - | O'Higgins | 0:1 | ||||
| 15. Round | 05/05/2012 | Deportes Iquique | - | Santiago Wanderers | 2:1 | ||||
| 16. Round | 12/05/2012 | Santiago Wanderers | - | Cobreloa | 1:3 |
Chile