| 3. Round | 27/06/2021 | Tacoma Defiance | - | Los Angeles Galaxy II | 2:0 | ||||
| 4. Round | 04/07/2021 | Las Vegas Lights FC | - | Tacoma Defiance | 1:0 | ||||
| 4. Round | 07/07/2021 | Orange County SC | - | Tacoma Defiance | 0:0 | ||||
| 4. Round | 12/07/2021 | Los Angeles Galaxy II | - | Tacoma Defiance | 1:1 | ||||
| 4. Round | 30/07/2021 | Tacoma Defiance | - | San Diego Loyal | 2:1 | ||||
| 5. Round | 01/08/2021 | Tacoma Defiance | - | New Mexico United | 0:0 | ||||
| 5. Round | 08/08/2021 | Tacoma Defiance | - | Oakland Roots | 3:1 |
Russia