| 4. Round | 02/10/2021 | KF Skënderbeu | - | FK Vllaznia | 0:0 | ||||
| 5. Round | 18/10/2021 | FK Vllaznia | - | Dinamo Tiranë | 6:3 | ||||
| 6. Round | 24/10/2021 | FK Kukësi | - | FK Vllaznia | 2:0 | ||||
| 7. Round | 30/10/2021 | FK Vllaznia | - | KF Tiranë | 0:2 | ||||
| 13. Round | 12/12/2021 | FK Vllaznia | - | KF Skënderbeu | 2:0 | ||||
| 18. Round | 30/01/2022 | KS Kastrioti | - | FK Vllaznia | 0:1 | ||||
| 23. Round | 03/03/2022 | FK Vllaznia | - | Dinamo Tiranë | 2:1 | ||||
| 24. Round | 07/03/2022 | FK Kukësi | - | FK Vllaznia | 0:0 | ||||
| 26. Round | 19/03/2022 | Egnatia Rrogozhine | - | FK Vllaznia | 3:0 |
Albania