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| 1st(1st leg) | Tuxtla FC | - | Club Irapuato | 1:0 | ||
| 2nd (2nd leg) | Club Irapuato | - | Tuxtla FC | 3:0 | ||
| 1st(1st leg): 29/11/2017 21:00 | 2nd (2nd leg): 03/12/2017 01:00 | Winner: Club Irapuato | ||||
| 1st(1st leg) | Inter Playa | - | Reboceros de La Piedad | 2:1 | ||
| 2nd (2nd leg) | Reboceros de La Piedad | - | Inter Playa | 2:0 | ||
| 1st(1st leg): 30/11/2017 01:00 | 2nd (2nd leg): 03/12/2017 02:00 | Winner: Reboceros de La Piedad | ||||
| 1st(1st leg) | Dorados UACH | - | Loros UCOL | 0:3 | ||
| 2nd (2nd leg) | Loros UCOL | - | Dorados UACH | 3:0 | ||
| 1st(1st leg): 30/11/2017 02:00 | 2nd (2nd leg): 02/12/2017 22:00 | Winner: Loros UCOL | ||||
| 1st(1st leg) | Deportivo Tepic | - | Tepatitlán | 0:0 | ||
| 2nd (2nd leg) | Tepatitlán | - | Deportivo Tepic | 4:0 | ||
| 1st(1st leg): 01/12/2017 02:30 | 2nd (2nd leg): 03/12/2017 22:00 | Winner: Tepatitlán | ||||
