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| 1st(1st leg) | Palmeiras | - | IAPE - MA | 3:0 (2:0) | ||
| 2nd (2nd leg) | IAPE - MA | - | Palmeiras | 0:2 (0:1) | ||
| 1st(1st leg): 15/10/2022 15:00 | 2nd (2nd leg): 22/10/2022 19:00 | Winner: Palmeiras | ||||
| 1st(1st leg) | Remo - PA | - | Internacional | 0:3 (0:1) | ||
| 2nd (2nd leg) | Internacional | - | Remo - PA | 4:0 (3:0) | ||
| 1st(1st leg): 16/10/2022 20:00 | 2nd (2nd leg): 22/10/2022 19:00 | Winner: Internacional | ||||
| 1st(1st leg) | Flamengo RJ | - | Fluminense - PI | 3:1 (1:0) | ||
| 2nd (2nd leg) | Fluminense - PI | - | Flamengo RJ | 0:1 (0:1) | ||
| 1st(1st leg): 17/10/2022 19:00 | 2nd (2nd leg): 23/10/2022 19:00 | Winner: Flamengo RJ | ||||
| 1st(1st leg) | Cruzeiro | - | Ceará - CE | 1:2 (0:1) | ||
| 2nd (2nd leg) | Ceará - CE | - | Cruzeiro | 4:1 (2:0) | ||
| 1st(1st leg): 19/10/2022 21:00 | 2nd (2nd leg): 24/10/2022 19:30 | Winner: Ceará - CE | ||||
